Sedating rat - ctc wstx sr validatingstreamreader
The three most abundant indole alkaloids are mitragynine, paynanthine and speciogynine.Mitragynine is the primary active alkaloid in the plant.
- In , used for treatment of diarrhea, worm infestation, and as analgesic and antipyretic.
Mambog is a forest tree that grows to a height of 10 to 25 meters.
Leaves are elliptic, 8.5 to 14 centimeters long, 5 to 10 centimeters wide, smaller at the ends of the branchlets, pointed at the tip, rounded or somewhat heart-shaped at the base, and hairy on the nerves beneath. Flowers are yellow, crowded in round, terminal inflorescences 3 to 5 centimeters long, the flowering heads consisting of up to 120 florets each.
Through action on centrally located opioid receptor, it inhibits gastric secretion and reduces pain response.
- At low doses, it produces increased alertness and energy, talkativeness and sociable behavior.
They are selective and full agonists of the µ-subtype opioid receptor MOR.
The receptor agonist effects are antagonized by the opioid receptor antagonist naloxone.
Fruit is oblong-ovoid and 5 to 7 millimeters long, with 10 ridges.
Different strains of kratom are grouped by leaf morphology: green veim (Yakyai), white vein (Tang gua), and red veins (Kan daeng).
- Chemical synthesis for several kratom alkaloids are too complex for economic production.
However, mitragine can be used as chemical precursor to the more potent 7-hydroxymitragynine.
- CNS effects may include kratom psychosis, hallucinations, delusion, and confusion.