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Recent studies have demonstrated that children with autism frequently have neuro-inflammatory and gastrointestinal inflammatory conditions occurring.Multiple studies demonstrate the beneficial effect of hyperbaric oxygen therapy in inflammatory conditions.
Mitochondria are the energy producing organelles of the body.Efrain Olszewer has pre- and post-angiograms documenting collateral circulation beginning as early as ten to twenty hours after initiating hyperbaric therapy for cerebral vascular disease and peripheral arteriosclerosis at pressures lower than 1.3 ATA It is known that one of the problems children with autism have is decreased blood flow to the brain (cerebral hypoperfusion).Therefore is has been speculated that angioneogenesis is the way that HBOT helps autism However, though angioneogenesis may be one mechanism by which children with autism are helped by HBOT, angioneogenesis may not be the primary mechanism by which HBOT works The amount of cerebral hypoperfusion in autistics compared to controls is about 8%, so a small increase in oxygen delivery may be all that is needed to overcome this deficit and show clinical benefit.A growing number of studies are focusing on the mitochondria and its relationship to many disorders The possibility exists that some autistic symptoms may occur if these organelles are dysfunctional or fewer in number than the number found in children without autism.HBOT may have the potential to activate dysfunctional mitochondria and/or to activate "dormant/idling cells" thereby allowing more "mitochondrial product" to be appreciated by the body.Then most parents will state what they are doing, e.g. Because dissolved oxygen is not confined to a hemoglobin molecule, it can go wherever "body water goes" and therefore reach 'deeper tissues' more easily and more consistently than ever before Because no test is able to predict which child may and which child may not respond to extra pressure and/or extra oxygen (in contrast to excessive oxygen), I let nature take its course and prescribe a clinical trial of HBOT for all my children Though I let "nature take its course", I would not consider prescribing or administering HBOT to children with autism unless there was good scientific evidence to support its use.
"we're using 1.5, 1.75, or 2.0 atmospheres in a hard chamber with 100% oxygen, or we're using a soft chamber (also referred to as a mild chamber) at 1.3 atmospheres 'with or without a mask' to which 'concentrated oxygen' is be supplied at concentrations varying from 24% to 70%." Conventional wisdom states that unless one receives HBOT in a hard chamber with 100% oxygen at atmospheric pressures greater than 1.5 ATA, little or no benefit will be seen. Fortunately such evidence does exist, the body of which continues to accumulate, and the mechanisms of action by which HBOT may work for children with autism, as described below, may already be outdated by the time you read this.
I explain to my patients that to get cockroaches out of the kitchen, I can either kill them with my shoe or turn on the light.
Interestingly it only takes a little bit of light for them to leave the room.
SPECT scans demonstrate the relative amount of blood that is able to reach the different areas in the brain.
Color coding allows easy visualization of what is occurring with blue areas representing little blood flow and yellow areas indicating normal blood flow.
The literature states that in order to kill viruses 100% oxygen at 2.7 ATA or above is required.